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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKI67
All Species:
6.06
Human Site:
T450
Identified Species:
19.05
UniProt:
P46013
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46013
NP_001139438.1
3256
358694
T450
P
F
L
T
L
W
L
T
Q
V
E
R
K
I
Q
Chimpanzee
Pan troglodytes
XP_508147
3257
358658
T450
P
F
L
T
L
W
L
T
Q
V
E
R
K
I
Q
Rhesus Macaque
Macaca mulatta
XP_001089669
2126
233775
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074586
3177
350846
N448
L
S
S
V
D
I
S
N
F
G
D
S
I
N
K
Rat
Rattus norvegicus
XP_225460
3119
343332
S447
G
L
S
S
I
D
I
S
N
C
G
D
S
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421822
2556
283606
Frog
Xenopus laevis
NP_001128553
2510
270869
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782273
1825
188999
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
55.1
N.A.
N.A.
43.1
43.1
N.A.
N.A.
22.4
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
98.7
57.3
N.A.
N.A.
58.2
57
N.A.
N.A.
38.5
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
34.9
P-Site Identity:
100
100
0
N.A.
N.A.
0
6.6
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
N.A.
N.A.
13.3
33.3
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
13
0
0
0
0
13
13
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% E
% Phe:
0
25
0
0
0
0
0
0
13
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
13
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
13
13
0
0
0
0
0
13
38
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
13
% K
% Leu:
13
13
25
0
25
0
25
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
13
0
0
0
0
13
13
% N
% Pro:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% R
% Ser:
0
13
25
13
0
0
13
13
0
0
0
13
13
0
0
% S
% Thr:
0
0
0
25
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
13
0
0
0
0
0
25
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _